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Selected leadership examples

Complex problems. Implementable solutions.

Six examples from 25 years across clinical medicine, drug development, global medical leadership and healthcare innovation.

These examples describe professional experience and transferable lessons. Confidential information, internal metrics and unsupported causal claims have been intentionally excluded.

AI · Medical intelligence

Turning scientific overload into actionable knowledge

Challenge

Dermatologists were facing an expanding volume of literature that was increasingly difficult to assimilate.

Response

Carlos helped lead an early AI-supported medical intelligence initiative with IBM Watson technology. The solution processed and summarized medical publications, supported by live scientific engagement that positioned physicians as co-creators rather than passive users.

Transferable lesson

The project demonstrated the potential of AI to shorten time-to-insight—and why technology maturity, timing and accountable ownership determine whether a promising innovation can scale.

Contemporary coverage

Translational medicine · Partnerships

Building an ecosystem for earlier clinical research

Challenge

Early research capability required alignment across scientific training, institutional infrastructure and the public-private environment.

Response

As part of Novartis Argentina’s scientific leadership, Carlos helped connect the Ministry of Science, Hospital Italiano and industry through a formal cooperation framework supporting researcher training, translational medicine and early clinical research capabilities.

Transferable lesson

Complex development barriers are rarely solved by one organization. Progress comes from creating a shared agenda, clarifying each partner’s contribution and building capability around a defined medical need.

Public partnership announcement

Digital health · Open innovation

Creating an innovation platform—not a one-off event

Challenge

Healthcare organizations can generate many ideas while lacking a repeatable route from unmet need to selection, development and implementation.

Response

Carlos led scientific and digital initiatives that brought medical leaders, researchers, technology specialists and entrepreneurs into structured programs including Innovation Week and the StartUp Summit.

Transferable lesson

Open innovation works when the problem, selection criteria, expert feedback and path to partnership are explicit. The event is only the visible moment; the operating model creates the value.

Novartis StartUp Summit

Real-world evidence · Psoriasis

Turning fragmented real-world data into decisive evidence

Challenge

In a highly competitive psoriasis market, an emerging narrative questioned whether secukinumab maintained its effectiveness over time. A unified European registry was not available, while country-level initiatives were difficult to combine because of heterogeneous endpoints, data-collection methods and investigator priorities.

Response

While leading Immunology and Dermatology for Novartis Region Europe, Carlos worked with Professor Matthias Augustin to develop a different evidence model: a meta-analysis integrating 43 real-world studies. Agile working methods and emerging technology-supported research workflows helped align the fragmented evidence and move the manuscript to editorial approval in record time.

Evidence generated

Published in JEADV, the analysis found secukinumab drug survival of 90% at three and six months and 80% at twelve months. At twelve months, 8% of patients had discontinued because of lack of effectiveness.

Transferable lesson

When a unified registry is unavailable, the solution may not be another study. Reframing the question and integrating existing evidence can generate a faster, stronger and more decision-relevant answer.

Peer-reviewed publication

Global medical strategy · Dermatology

Leading global medical strategy for a transformative biologic

Challenge

As dupilumab expanded across dermatologic diseases, patient populations and stages of the product lifecycle, the organization needed a coherent global medical strategy connecting disease biology, evidence generation, external insights and launch execution.

Response

As Vice President and Global Medical Dermatology Head, Carlos led the dermatology medical strategy and global team supporting the product’s lifecycle development. His remit included evidence planning, launch readiness, scientific engagement, insight generation and cross-functional alignment across indications and regions. Dermatology remained a central clinical engine of the dupilumab type 2 inflammation platform.

Evidence generated

In 2025, during Carlos’s tenure leading Global Medical Dermatology, Dupixent was named Best Biotechnology Product by the Prix Galien USA, recognizing its groundbreaking science and transformational impact across rare and common allergic and atopic diseases.

Transferable lesson

Global medical strategy is not the coordination of multiple indication plans. It is the ability to build one scientific platform that generates credible, disease-specific evidence and guides decisions across the product lifecycle.

2025 Prix Galien USA laureates

Clinical science · Evidence strategy

Connecting academic depth with development decisions

Challenge

Development teams may need a clearer connection between disease biology, real clinical practice and the evidence required to differentiate an asset.

Response

Carlos combines training in internal medicine and dermatology with dermatopathology, research, teaching and senior pharmaceutical leadership to examine a program from multiple perspectives.

Transferable lesson

Clinical depth changes the questions asked early—helping identify relevant endpoints, evidence gaps and implementation barriers before they become expensive development problems.

Selected clinical research

A focused first conversation

What medical decision is slowing your next move?

Share the asset, challenge or decision. We will identify whether a strategic session, project or fractional role is the right fit.

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